Antifungal chromans inhibiting the mitochondrial respiratory chain of pea seeds and new xanthones from Calophyllum caledonicum
Article Abstract:
The antifungal activity of two new xanthones, isolated from the hexane-soluble extract of the stem bark of a Calophyllum caledonicum, and seven other known compounds, against the growth of the human pathogenic fungus Aspergillus fumigatus was investigated. Tests showed that some of the compounds markedly reduced the respiration of pea seed mitochondria.
Publication Name: Planta Medica
Subject: Pharmaceuticals and cosmetics industries
ISSN: 0032-0943
Year: 2003
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A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats
Article Abstract:
Paeoniflorin is a bioactive monoterpene glucoside in Paeoniae Radix (PR), the roots of Paeonia lactiflora (Ranunculaceae). Investigations reveal that rats and pigs are appropriate models for investigating the metabolism and pharmacokinetics of paeoniflorin.
Publication Name: Planta Medica
Subject: Pharmaceuticals and cosmetics industries
ISSN: 0032-0943
Year: 2003
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Cardiovascular effects induced by reticuline in normotensive rats
Article Abstract:
The cardiovascular effects of reticuline in normotensive rats are demonstrated using a combined in vitro and in vivo approach. Results showed that reticuline induces hypotension in rats, which is probably due to a decrease in peripheral vascular resistance.
Publication Name: Planta Medica
Subject: Pharmaceuticals and cosmetics industries
ISSN: 0032-0943
Year: 2004
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