Deadly dialogue: Healthy tissue may inadvertently call in tumors
Article Abstract:
Scientists are studying the phenomenon of metastasis and have revealed how a distant tumor cells interact with future sites of metastasis in the lungs through a signaling mechanism involved in immune response to pathogens. Yoshiro Maru and group from Tokyo Women's Medical University have presented a novel concept that tumor metastasic potential might be dependent on the tumor-initiating ability of the cancer cells, and also on the existence of hot spots within each specific organ that are receptive to metastatic cells.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 2007
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Here come the X-mice: A mutant mouse army to battle disease
Article Abstract:
The Knockout Mouse Project (KOMP) launched in 2007 is an ambitious plan to learn the function of every gene in the lab mouse Mus musculus, with the aim of understanding comparable genes in humans. The US component of the multinational effort will target about 10,000 mouse genes, and will require the production of a large living database of cell lines of mutant mice, each carrying one disabled or 'knocked out' gene, for the purpose of research.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 2007
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Repair workers within
Article Abstract:
Several patients treated with bone marrow transplants have shown that an infusion of healthy stem cells could regenerate a failing body part. As a result, the haematopoietic stem cells in the marrow that normally produce billions of blood and immune cells daily needed replacing.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 2005
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