Evolution of a practical total synthesis of ciguatoxin CTX3C
Article Abstract:
The highly convergent total synthesis of CTX3C is improved and refined to a satisfactory level in terms of overall stereoselectivity and efficiency. The molecules synthesized will accelerate development of strategies to control ciguatera and lead to the creation of voltage-sensitive sodium channels (VSSC) probes that may elucidate VSSC-ligand interactions at the molecular level.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2004
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Iron-sulphur cluster biosynthesis: toward an understanding mof cellular machinery and molecular mechanism
Article Abstract:
The proteins involved in the biosynthesis of 'simple' Fe-S clusters are identified. It was observed that the IscU (or ISU) family of proteins serves a key role as scaffolding proteins on which [2Fe-2S] building blocks are assembled prior to transfer to final apo target proteins.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2004
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A conversation on VB vs MO theory: a never-ending rivalry?
Article Abstract:
Valence bond (VB) theory and molecular orbital (MO) theory are the two general theories provided by the quantum mechanics. The comparative analysis of the two is presented in order to describe the bonding in molecules.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2003
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