The whole lactose repressor

Article Abstract:

Researchers have made great strides in understanding the structure and functions of the tetrameric lactose repressor gene and its complexes. The research has contributed to a better understanding of the regulation of genetic expression.

History, Genetic research, Molecular genetics

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Expansion of the allelic exclusion principle

Article Abstract:

Certain cells use only one copy of a gene to encode for RNA and protein. Not only is the other allele not expressed, but other genes from the same family are excluded. Research on the mechanism of monoallelic transcription is presented.

Reports, Genetic transcription, Transcription (Genetics), Immunological research, Immunologic research

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DNA looping and the lac repressor-CAP interaction

Article Abstract:

A structural model for binding sites for lac repressor (lacR) with CAP bound inside a DNA loop and LacR bound on the opposite side has been proposed. Arguments for and against this interpretation of data are presented.

Binding sites (Biochemistry), Active sites (Biochemistry)

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