A prospective, open-label trial of ondansetron in adolescents with alcohol dependence

Article Abstract:

Ondansetron is shown to be effective in the treatment of early-onset adult alcohol dependence. Preliminary data from studies conducted suggest that ondansetron is safe and well tolerated in adolescents with alcohol dependence and findings of decreased drinking underscore the need for future double-blind, placebo-controlled studies in this adolescent population.

Adults, Patient outcomes, Alcohol use

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Reductions in and relations between "craving" and drinking in a prospective, open-label trial of ondansetron in adolescents with alcohol dependence

Article Abstract:

An open-label study is conducted on adolescents with alcohol dependence using ondansetron, which is a 5-HT(sub 3) antagonist. Results show that ondansetron reduces 'craving' in the subjects as measured by the Adolescent Obsessive-Compulsive Drinking Scale (A-OCDS) and that irresistibility and A-OCDS scores decrease significantly during treatment.

Health aspects, Care and treatment, Alcohol and youth, Juvenile drinking

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Treatment studies involving adolescents with drug and alcohol disorders

Article Abstract:

Studies are conducted involving adolescents with alcohol and other substance use disorders. Data on adolescent substance use are collected psychometry studies, medication studies and treatment-related studies are conducted.

Health Care and Social Assistance, HEALTH SERVICES, Labor Distribution by Employer, Health Statistics, Statistics, Medical statistics, Drugs and youth, Juvenile drug abuse

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