Open trials as a method of prioritizing medications for inclusion in controlled trails for cocaine dependence

Article Abstract:

Brief, open, clinical trials are proposed to improve the process of selecting medications for large-scale clinical trials. A method of open trials to identify medications that could be useful in the treatment of cocaine dependence is reported. Medications are evaluated in small trials and their efficacy is measured in relation to a comparison group. The study shows how important the inclusion of a comparison group in pilot trials is, although it increases the risk of introducing bias based on baseline differences among groups.

Research, Compulsive behavior, Cocaine abuse

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Treatment outcomes for alcohol dependence among middle-aged and older adults

Article Abstract:

A prospective naturalistic study is conducted to examine differences in the clinical presentation and treatment outcomes of older adults with a diagnosis of alcohol dependence compared to middle-aged adults. No significant different outcomes are found in abstinence rates at 1 month, older adults engaged in formal post-discharge aftercare less than middle-aged adults.

Individual and family services, Other Individual and Family Services, Alcoholics Rehabilitation, Middle aged persons, Health aspects, Care and treatment, Analysis, Alcoholism, Alcoholism treatment

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