A possible prebiotic synthesis of pantetheine, a precursor to coenzyme A

Article Abstract:

Heating a solution containing 1 millimol each of cysteamine, beta-alanine and pantoyl lactone at 40 degrees Celsius produces pantetheine, a precursor for coenzyme A. Formation of amide bonds at temperature as low as 40 degrees Celsius supports the participation of the coenzyme A and pantetheine in the earliest metabolic systems.

Coenzymes, Amino acid metabolism

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Functional proteins from a random-sequence library

Article Abstract:

Research is presented describing the frequency of functional proteins from random-sequence libraries, and their similarity to the frequency observed in equivalent RNA libraries. Researchers used an in vitro selection of messenger RNA displayed proteins in order to sample a lot of separate random sequences.

Observations, Proteins, Protein research, Amino acid sequence, Amino acid sequencing

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Molecular messages

Article Abstract:

The author has investigated biopolymer sequences. He discusses the nature of the information content of these sequences.

United States, Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, Physiological aspects, Genetic aspects, DNA, Genomes, RNA, Biopolymers, Molecules, Chemical properties

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