ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion
Article Abstract:
The study of regulated fusion of secretory granules having plasma membrane in secretory cells reveals that the use of ATP in exocytotic pathway requires the lipid kinase-mediated phosphorylation. ATP, Ca2+ proteins, membrane proteins and cytosolic proteins are essential for the regulated fusion of the secretory granules. The ATP associated mechanisms require three different cytosolic PEP proteins, which consist of I phosphatidylinositol-4-phosphate 5-kinase, and thereby the process of phosphorylation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution
Article Abstract:
The imaging of single fluorescently labelled myosin molecules and identification of individual ATP turnover reactions are possible with in vitro assays improved through epifluorescence and total internal reflection microscopies. This technique is used for video-rate imaging of single molecules in aqueous solution and so can observe ATP hydrolysis.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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