An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells
Article Abstract:
Researchers have shown that the related Arabidopsis GBF protein GNOM-LIKE1 (GNL1) has an ancestral function at the Golgi but is needed for selective internalization from the plasma membrane in the presence of brefeldin A (BFA). GNL1 is found to be BFA-resistant GBF protein that has functioned with a BFA-sensitive guanine-nucleotide exchange factors for ADP-ribosylation factor GTPase (ARF-GEF) both at the Golgi and in selective endocytosis, but not in recycling from endosomes.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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The Golgi grows up
Article Abstract:
Cisternal maturation model is discussed in brief which proposes that the cisternae progress through the Golgi, gradually moving through the stack as new layers form at the cis face and old layers disperse from the trans face and that they carry the secretory proteins with them. Scientists have exploited some innovative microscopy to produce striking images that purport to show direct evidence for cisternal maturation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Live imaging of yeast Golgi cisternal maturation
Article Abstract:
High-speed three-dimensional confocal microscopical measurements show that yeast Golgi cisternae change the distribution of resident membrane proteins from the cisternal nature to the trans overtime, as proposed by the maturation model in a very dynamic way. Improvement of the imaging methodology could provide an unambiguous understanding of the conveyance of membrane components between cisternae.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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