Assignment of circadian function for the Neurospora clock gene frequency
Article Abstract:
Circadian rhythms are driven by endogenous oscillators, and synchrony with zeitgeber comes from entrainment of the oscillator. Inputs can be circadianly regulated, with outputs fed back on the oscillator. Under or overexpression of a gene product can lead to arrhythmicity. Traditional circadian entrainment protocols were used on a genetic model system, Neurospora crassa. The FRQ protein was not required for entraining an oscillator with generic circadian properties, but the circadian clock cannot synchronize to light:dark cycles without FRQ.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
A mammalian gene with introns instead of exons generating stable RNA products
Article Abstract:
Seven fibrillarin-associated snoRNAs have been found to be encoded within introns of the compact mammalian U22 host gene (UHG). The unique snoRNAs, named U25-U31, show extensive complementarity to various segments of the mature rNAs. The spliced UHG RNA is poorly conserved between human and mouse, is not promising for protein coding and has a short life, showing that introns specify the functional products of UHG.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
View of a mouse clock gene ticking
Article Abstract:
Issues are presented concerning the observation of rhythmic expression of the mPer1 clock gene in a mouse's brain. The monitoring of real-time gene expression in the transgenic mouse is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Circadian oscillation of a mammalian homologue of the Drosophila period gene. Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS
- Abstracts: Background inhibition to the fore. Stem cells on the brain. Moving forward by looking away
- Abstracts: Genetics, taxonomy and conservation of the threatened California Gnatcatcher. Dragonfly pond restoration promotes conservation awareness in Japan
- Abstracts: The nature of the solar wind. Rapid acceleration of the polar solar wind