BSE transmission to macaques

Article Abstract:

Intracerebral inoculation of cynomolgus macaques with bovine spongiform encephalopathy (BSE) cattle brain homogenate reveals spongiform changes and plaque morphology similar to human cases of variant of Creutzfeldt-Jakob disease (vCJD). Immunoblot studies show accumulation of abnormal prion protein resembling the vCJD pattern with more protein in the cerebellum than in the forebrain. The abnormal behavioral signs exhibited by the macaques several weeks after inoculation include depression, voracious appetite and ataxia. The study reinforces the link between the BSE agent and vCJD.

Analysis, Observations, Bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, Macaques, Disease susceptibility

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Don't leave it to the market-place

Article Abstract:

The British government's efforts to privatize the management of national observatories have proved to be futile. The proposed step is the result of the government's attempt to make the maximum utilization of the scarce resources for research. The main obstacle to privatization is the need to provide for the pension rights of employees, which require several million pounds. Alternative ways to achieve the government's desire to ensure cost-effective spending of public money on science are being explored.

United Kingdom, Mergers, acquisitions and divestments, Science and technology policy, Privatization, Privatization (Business), Astronomical observatories

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