Catalytic competition for cells
Article Abstract:
Ways of evolving proteins, and assessing the vast number of variants needed to identify those with novel enzymatic activity, are themselves evolving. Oil droplets containing basic cell machinery provide a promising approach whereby the IVC system preserves the cell's means of linking DNA to protein, and then adds on in vitro chemistry to create the evolutionary pressure.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Article Abstract:
The generation of a genome-scale library of endoribonuclease-prepared short interfering (esi)RNAs from a sequence-verified complementary DNA collection representing 15497 human genes, is reported. New aspects of cell division are revealed and esiRNAs are established as a versatile approach for genomic RNAi screens in mammalian cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Spring theory
Article Abstract:
Molecular biologists are becoming interested in the mechanics of single molecules as it helps in understanding how the cells manage billions of bits of information stored on vast polymer strings. Physicists are also trying to study the packaging of all DNA into the nucleus of cell.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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