Control of RNase E-mediated RNA degradation by 5'-terminal base pairing in E. coli
Article Abstract:
RNase E, an endoribonuclease from the messenger RNA (mRNA) of the bacterium Escherichia coli, tends strongly to separate only RNAs with several unpaired nucleotides at the 5' end. This is the first indication of what factors determine how quickly bacterial mRNA breaks down and ceases to affect bacterial genetic expression. RNase E appears to derive this selective property from the inhibitory function of the 5'-terminal stem-loop.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
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Gene expression and mRNA
Article Abstract:
Gene expression is significantly effected by the stability of messenger RNA between synthesis and decay. An evaluation of five pts promoters found that different promoters generate different degrees of stability. Therefore, the various promoters appear to have a large impact on the control of pts expression.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal
Article Abstract:
The activation of the messenger RNA (mRNA) by the bacterial enzyme, RppH through the removal of 5' pyrophosphate is discussed. The findings prove that RppH highly affects the invasiveness of the bacterial pathogens.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2008
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