Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex
Article Abstract:
The crystal structure of full-length yeast heat shock protein of 90 kDa (Hsp90) in complex with ATP analogue and the co-chaperone p23/Sba1 is presented. The closed Hsp90 would not enclose its client proteins but provides a bipartite binding surface whose formation and disruption are coupled to the chaperone ATPase cycle.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex ad WASP/Scar proteins
Article Abstract:
A new study uses fluorescence microscopy to observe actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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