Enzymes play molecular tag
Article Abstract:
The RAF enzymes are central intermediates in fundamental signalling cascade, transmitting signals from RAS to the downstream enzymes MEK and ERK. The activation of RAF is typically initiated by an interaction with RAS, which leads to RAF relocating from the cellular cytoplasm to the plasma membrane.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB
Article Abstract:
Topoisomerase (TopIB) releases supercoils by a swivel mechanism that involves friction between the rotating DNA and the enzyme cavity. The enzyme is found to be torque-sensitive, as the mean number of supercoils per step increases with the torque stored in the DNA.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Understanding and tuning the epitaxy of large aromatic adsorbates by molecular design
Article Abstract:
Site recognition in non-templated organic epitaxy is explained. Diagrams illustrating the molecule substrate interaction and the intermolecular interaction which do not cause mutual frustration in epitaxial site recognition are presented.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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