Glutamate receptors at atomic resolution

Article Abstract:

The amino-acid glutamate receptor ion channels at synapses throughout the brain and spinal cord consist of discrete ligand-binding, ion-channel, modulatory and cytoplasmic domains. Crystallographic studies that exploit this unique architecture aid structural analysis of the ligand-binding core, but the question of the allosteric mechanisms by which individual domains communicate and function in an intact receptor is to be answered.

Glutamate, Amino acids, Structure

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Greater expectations

Article Abstract:

The study aims to explore how one can understand the bewildering complexity of the humans of pre-Columbian South America. Julian Stewart sketched out the historical development implications of his classification, putting Central Andean civilizations at the top, and descending through circum-Caribbean/sub-Adean, to tropical forest peoples, and with 'marginal' tribes at the bottom.

Uruguay, Excavations (Archaeology), Prehistoric archaeology

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Gate expectations

Article Abstract:

The opening and closing or 'gating' of ion channels in response to a specific stimuli is considered crucial for the cell to function to control its internal environment. An attempt made to describe how toxins isolated from the venom of tarantulas interact with two different types of ion channel is also presented

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