How does variation count?
Article Abstract:
Recent research on the variation and evolution of viruses was the subject of an EMBO workshop held in Grignon, France from Jul 7 to Jul 11, 1992. Participants learned of new techniques for studying viral diseases and how viruses evolve into new varieties. Complicated but usable experimental viral systems were described that could verify or falsify current theories of viral population dynamics. In addition, participants learned that not only the human immunodeficiency virus but all RNA viruses have high rates of mutation and recombination.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
Closing the joint
Article Abstract:
It has been established that a cellular damage-sensing system is implicated in completing retroviral integration. This research involved seeking to infect cells defective in a damage-sensing protein complex with a number of different retroviral vectors. It was concluded that DNA-dependent protein kinase (DNA-PK) is required to complete integration, probably through repairing the gapped DNA left by integrase. The theory that DNA-PK is directly involved in integration has attracted controversy.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
Lines drawn in epitope wars
Article Abstract:
A study of the host immune response in coping with HIV infection and the cytotoxic T cells response in two infected haemophiliacs shows that the HIV virus was bonded to a single epitope for one patient but for the other patient, a complex figure of shifting immunodominance with the coming and disappearing variant viruses is detected. For the first patient the disease development is slow which likely relates to a fruitful response against a comparatively constant epitope.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: North Carolina wolf country. Bliss in the bottomlands. Acrobat of the Appalachians: what role does the tiny flying squirrel play in the mile-high forests of North Carolina?
- Abstracts: Creation in silicon. Lighter than air. Formally speaking
- Abstracts: Observation of Feshbach resonances in a Bose-Einstein condensate. Skyrmions in a ferromagnetic Bose-Einstein condensate
- Abstracts: Variation and vaccination. Getting into the liver
- Abstracts: How to publish the unpalatable? Polite row about models in biology. Systematic errors in 'Big G'?