Sticking to the point
Article Abstract:
Macrophage inflammatory factor may be one of the adhesion triggers influencing the activity of integrins in promoting the adhesion of leukocytes to the endothelium of postcapillary venules. A consensus model has emerged in which members of the selectin and integrin families are part of a two-step process required for leukocyte extravasation. Selectins promote the transient adhesion of leukocytes to the epithelium by slowing their passage through postcapillary venules. This transient adhesion is then intensified by the action of integrins.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
Colonial match and mismatch
Article Abstract:
The ability of an individual to distinguish tissues of another individual from its own is a fundamental characteristic of multicellular animals. This process, known as allorecognition, is seen in the success or failure of skin grafts and organ or bone-marrow transplants in humans and other vertebrates.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Lifespan of human lymphocyte subsets defined by CD45 isoforms. Evidence for a viral superantigen in humans
- Abstracts: Russian academy makes deal with US company on journals. Nature in 2003. Publishers go head-to-head over search tool
- Abstracts: Cell-to-cell spread of calcium signals mediated by ATP receptors in mast cells. ATP joins the fast lane
- Abstracts: Chemokines and leukocyte traffic. Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1
- Abstracts: Tilt and northward offset of Cordilleran batholiths resolved using igneous barometry. A refractory HIMU component in the sources of island-arc magma