Max in a complex affair
Article Abstract:
A protein that fastens to a specific DNA and takes charge of the polymerization of RNA is a transcription factor called max. Proteins must distinguish and connect to definite DNA sequences after the interaction of amino acid side-chains with nucleotide bases of specific DNA sequences. The helix-loop-helix (HLH) is marked by two amphipathic alpha-helices linked by a loop. Two alpha-helices segregated by a loop is typical of a Max homodimer-DNA structure. The peculiarities of Max homodimer is how it recognizes its DNA target and the similarity between Max-DNA structure and GCN4bZIP-DNA complex.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
DNA-binding properties of the yeast SWI/SNF complex
Article Abstract:
A study was conducted on the binding effects of the purified yeast SWI/SNF complex on DNA. A gel retardation assay was used to test the DNA-binding properties of the yeast. Results showed that the SWI/SNF complex binds with high affinity to promoter sequences from genes that are both dependent on and independent from the complex. The apparent binding constant was estimated at 1-9 times 10(super -9)M.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Selection of RNA-binding peptides in vivo. Moonlighting at the pole. RNA enzymes for RNA splicing
- Abstracts: Martians in a deep freeze. Dead trees tell tales. You can pile it only so high
- Abstracts: Earth's core not so hot. Melting of iron at the physical conditions of the Earth's core. Geodynamic estimates of the viscosity of the Earth's inner core
- Abstracts: Surface ozone depletion in Arctic spring sustained by bromine reactions on aerosols. Ideas flow on Antarctic vortex
- Abstracts: Running rings around modellers. The enigma of Jupiter's ring. Gravitational wakes in Saturn's rings