MicroRNA silencing through RISC recruitment of elF6
Article Abstract:
The study results related to the human RISC (RNA-induced silencing complex) associates with a multiprotein complex containing MOV10 which uncovers an evolutionarily conserved function of the ribosome anti-association factor elF6 in miRNA-mediated post-transcriptional silencing is presented.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
CRD-BP mediates stabilization of [beta]TrCP1 and c-myc mRNA in response to [beta]-catenin signalling
Article Abstract:
CRD-BP mediates stabilization of [beta]TrCP1 and c-myc mRNA in response to [beta]-catenin signaling. CRD-BP induction in the upregulation of [beta]TrCP1, in the activation of dimeric transcription factor and in the suppression of apoptosis is implicated in the suppression of cancers.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
The microprocessor complex mediates the genesis of microRNAs
Article Abstract:
It is shown that human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, and the smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Survival of scaup ducklings in the boreal forest of Alaska. Survival of ducks banded in the Boreal forest of Alaska
- Abstracts: Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
- Abstracts: Understanding the valency of rare earths from first-principles theory. Magnetic trapping of rare-earth atoms at millikelvin temperatures
- Abstracts: The expanding electronic universe. High-energy colliders and the rise of the standard model. Colliders race for the Higgs
- Abstracts: The genome of the social amoeba dictyostelium discoideum. Facultative cheater mutants reveal the genetic complexity of cooperation in social amoebae