Myelin-like sheaths in copepod axons
Article Abstract:
It appears that nerve fibres of many copepods are designed for rapid signalling. They have well-developed myelin-like sheaths, which reduce a copepod's reaction time to predatory attack and may therefore be vital for the survival of the large copepod populations found in dangerous oceanic ecosystems. In copepods with the myelin-like sheaths, almost all axons of both sensory and motor nerves of the first antenna are ensheathed. Copepod myelin has concentrically arranged layers of membrane around the axon.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia
Article Abstract:
N-methyl-D-aspartate (NMDA) glutamate receptors mediate Ca(super 2+) accumulation in central myelin in response to chemical ischaemia in vitro. The Ca(super 2+) increase mediated in large part by activation of myelinic NMDA receptors suggest a mechanism of axo-myelinic signalling, representing a potentially important therapeutic target in multiple sclerosis and aspects of ischaemic brain injury in which demyelination is a prominent feature.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Assault on the guardian
Article Abstract:
The contribution of autoimmunity to a protein known as [alpha]-B-crystallin (CRYAB) on inflammatory injury of the central nervous system, such as multiple sclerosis (MS), is described. It is shown that polymorphisms in the promoter genes encoding CRYAB might affect disease severity and a suspected mediator of damage in MS can use CRYAS as a substrate, offering another way in which inflammation might reduce the protein's availability.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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