NMR structure of a receptor-bound G-protein peptide
Article Abstract:
Transferred nuclear Overhauser effect nuclear magnetic resonance spectroscopy was used to study the structure of the active interface between rhodopsin and the G-protein transducin. Results revealed a peptide of 11-amino acids found at the C terminus of the Gt alpha-subunit linked to rhodopsin which imitated G protein in stabilizing metarhodopsin II. The peptide was also found to be capable of binding rhodopsin in its excited and unexcited form. An G-protein activation process involving agonist-stimulated receptors is suggeted by differences observed in the conformation of both bound forms.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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Molecules join the assembly line
Article Abstract:
Issues concerning techniques of pattern making using molecular building blocks in nanotechnology are discussed. Particular attention is given to ways of assembling molecules and to possibilities of constructing electronic devices based on molecules.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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Solid-state NMR determination of the secondary structure of Samia cynthia ricini in silk
Article Abstract:
Research is presented concerning the influence of the secondary structure which governs the elasticity and tensile strength of silk. NMR studies were used to determine the secondary structure of the silk of the silkworm, Samia cynthia ricini.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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