Notch signalling limits angiogenic cell behavior in developing zebrafish arteries

Article Abstract:

Notch signalling is an essential factor for restricting angiogenic cell behavior to tip cells in developing segmental arteries in the zebrafish embryo. The results have indicated that proper specification of cell identity, position and behavior in a developing blood-vessel sprout is needed for normal angiogenesis and has also implicated the Notch signalling pathway in this process.

Massachusetts, Analysis, Physiological aspects, Growth, Gene expression, Zebra fish, Zebra fishes, Company growth, Endothelial growth factors

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Sperm-egg fusion unscrambled

Article Abstract:

The new discovery of sperm-egg fusion is of a sperm-specific protein called Izumo, a protein named after the Japanese shrine to marriage and the evidence that it is required for fusion. The findings raise the exciting possibility that, because Izumo is sperm-specific and extracellular, this protein and its interacting partners could be new targets for non-hormonal contraception.

Japan, Fertilization in vitro, Human, Human fertilization in vitro

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Molecular monogamy

Article Abstract:

Cells will stop functioning if the interactions between cellular proteins are not highly specific. This specificity evolving in yeast is revealed by some clever protein- manipulating experiments.

Food preparations, not elsewhere classified, All Other Miscellaneous Food Manufacturing, Yeast, Yeast (Food product)

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