Old head on young shoulders
Article Abstract:
The developmental expression of AmphiOtx, the amphioxus member of the Otx homeobox gene class, is described to determine the origins and antiquity of characters within the head of vertebrates. The AmphiOtx is a cephalochordate which retained characteristics of vertebrate ancestors. At early developmental stages, there is strong expression in the anterior neural plate and the underlying mesendoderm. At later developmental stages, Otx gene expression is limited to specific cell groups in the anterior neural tube of both vertebrates and amphioxus.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
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Origin of patterning in neural tubes
Article Abstract:
The ascidian, Halocynthia roretzi, Pax gene HrPax-37 is a descendant of vertebrate Pax-3 and Pax-7, and the genes have similar functions in the differentiation of dorsal neural tube in vertebrates. The spatial and temporal expression of HrPax-37 at various embryonic stages provides evidence for the segmental organization of neural tube. The dorsal specification, and the segmental organization were established during emergence of the dorsal tubular nervous system in the chordates' ancestors.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
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The future of evolutionary developmental biology
Article Abstract:
There has been reconciliation between the two fields of evolutionary biology and developmental biology in the past 14 years. The three main factors contributing to the emergence and growth of evolutionary developmental biology have been the discovery that animal uses similar genes for similar developmental purposes, the rise of molecular phylogenetics, and technical advances in molecular biology.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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