Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper
Article Abstract:
The structure of a streptococcal (S. dysgalactiae) FnBP peptide (B3) 6,7 in complex with the module pair 1 F1 2 F1 is depicted. 1F1 and 2F1-binding motifs in B3 forms a tandem beta-zipper that is used by pathogenic bacteria to attach to human fibronectin.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Fibronectin requirement in branching morphogenesis
Article Abstract:
It is shown that extracellular matrix protein fibronectin 4,5 is essential for cleft formation during the initiation of epithelial branching. The fibronectin requirement in branching morphgenesis, which is characteristic of many organs, is explained.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin
Article Abstract:
A report is presented on specific molecular slip bond that was broken repeatedly. Mechanical forces on matrix-integrin-cytoskeleton linkages are very important for cell viability, morphology and organ function.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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