Photoinduced electron transport across a lipid bilayer mediated by C70
Article Abstract:
Carbon 70 (C70), a fullerene molecule, can effect electron transport more efficiently than previous artificial molecules due to its ability to act as a photosensitizer. C70 thus uses light to cause donor molecules to give up electrons. Moreover, C70 is a significant improvement over earlier mediators of electron transport because it can move electrons across a lipid bilayer membrane. These properties endow C70 and future fullerenes with great promise as transmembrane electron-transport systems.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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Lipid membranes shape up
Article Abstract:
Transmission of substances across cell membranes requires the pinching-off and subsequent merging of a vesicle from its donor and acceptor membrane. The GTP-hydrolysing protein dynamin is implicated in membrane constriction and fission although its role is unclear. A new study suggests that dynamin acts indirectly by activating an unknown effector system. Results show that dynamin works with endophilin I, a presynaptic protein of unknown function, to mediate synaptic vesicle formation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Crystal structure of the annexin XII hexamer and implications for bilayer insertion
Article Abstract:
The 2.8 angstrom resolution atomic structure of the annexin XII hexamer reveals a 210K homohexamer with 3-2 symmetry in the asymmetric unit. The 70-angstrom-thick hexamer forms a concave disk with a diameter of 100 angstroms. Six Ca2+ ions are present in the hexamer formation. A novel model for annexin-phospholipid bilayer interaction indicates that Ca2+ sites present on the perimeter of the hexamer regulate the hydrophilic insertion of the protein complex into the phospholipid layer.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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