Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
Article Abstract:
A study to show that Sgo1 recruits to centromeres a specific form of protein phosphatase 2A (PP2A) in both fission and budding yeast is presented. The data are consistent with the notion that efficient cleavage of Rec8 requires phosphorylation of cohesion and that this is blocked by PP2A at meiosis I centromeres.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Cohesin mediates transcriptional insulation by CCCTC-binding factor
Article Abstract:
The article discusses association of the cohesin-binding sites in human genome with the CCCTC-binding factor (CTCF), protein required for the process of transcriptional insulation. The findings prove that cohesin mainly helps in mediating transcriptional insulation by the CCCTC-binding factor.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2008
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S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex
Article Abstract:
The checkpoint regulatory mechanism plays an important role in maintaining the integrity of the genome. The checkpoint regulatory proteins Tof1 and Mrc1 are explained to interact directly with the DNA replication machinery.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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