Arrangement of RNA and proteins in the spiceossomal U1 small nuclear ribonucleoprotein particle
Article Abstract:
Research is presented concerning the development of techniques which enable a structural model of the three-dimensional protein and RNA arrangements in U1 snRNP to be derived in eukaryotic cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts
Article Abstract:
Research is presented concerning the prevention of read-through transcription from small nuclear RNA genes and yeast small nucleolar RNA into adjacent genes through the action of a cis-acting element.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
Article Abstract:
The lifespan of normal human cells can be greatly extended by activation of the chromosome end-replicating enzyme telomerase, associated with human cancers. An examination of eukaryotes in yeast shows that telomerase has an RNA subunit but little is known about its components. A new study shows that Saccharomyces cerevisiae telomerase RNA has a binding site for the Sm proteins and a 5'-2,2,7-trimethylguanosine cap, both an indication of small nuclear ribonucleoprotein particles involved in nuclear messenger RNA splicing. The study support a model in which RNA polymerase II and 7-methylguanosine-capped transcribe telomerase RNA.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Single-molecule studies of the effect of template tension on T7 DNA polymerase activity. The bacteriophage phi-29 portal motor can package DNA against a large internal force
- Abstracts: Irruptive potential in roe deer: Density-dependent effects on body mass and fertility. Does recreational hunting of lynx reduce depredation losses of domestic sheep?
- Abstracts: Field trials of line transect methods applied to estimation of desert tortoise abundance. Null hypothesis testing: problems, prevalence, and an alternative
- Abstracts: Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms
- Abstracts: Archaeal dominance in the mesopelagic zone of the Pacific Ocean. Genomic perspectives in microbial oceanography