Rhapsody in G proteins
Article Abstract:
Guanine-nucleotide-binding (G) proteins regulate cellular processes. Both heterotrimeric G proteins and small GTPases can be regulated by way of guanine-nucleotide-exchange factors and by hydrolysing GTP to GDP. Mochizuki and colleagues and Jordan and colleagues report a way in which heterotrimeric G proteins can regulate Rap1, a small GTPase. They show that the alpha-subunits of Gi and Go form a complex with Rap1GAP.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Glowing switches
Article Abstract:
Issues are presented concerning the fluorescent resonance energy transfer techniques which were utilized for the analysis of the activation of a GTPase enzyme, named Ras, in real space and time. Previous activation had been biochemical.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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Spatio-temporal images of growth-factor-induced activation of Ras and Rap1
Article Abstract:
Research is presented concerning the investigation of spatio-temporal images of the growth-factor-induced activation of Rap1 and Ras through the utilization of fluorescent resonance energy transfer based sensors.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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