The structure and evolution of centrometric transition regions within the human genome
Article Abstract:
A detailed analysis of the structure and assembly of all human pericentromeric regions is presented, which will assist in understanding the structure and evolution of the centrometric transition regions within the human genome. Results indicate that the distribution of the duplicated segments among the pericentromeric regions is nonrandom, which suggests that some regions may have served as preferential acceptors of euchromatic deoxyribonucleic acid (DNA).
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Genomes for medicine
Article Abstract:
High-quality annotation is required of all the functionally important sequences and the variations within them that contribute to health and disease. The possibility of unlimited medical sequencing is the most striking future clinical application arising from the reference human genome sequence.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
A high-resolution map of active promoters in the human genome
Article Abstract:
A genome-wide map of active promoters in human fibroblast cells is described. The results provide a global view of the functional relationships among transcriptional machinery, chromatin structure and gene expression in human cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Shotgun sequence assembly and recent segmental duplications within the human genome. The DNA sequence of human chromosome 7
- Abstracts: Production and evolution of light elements in active star-forming regions. Dodecahedral space topology as an explanation for weak wide-angle temperature correlations in the cosmic microwave background
- Abstracts: Structural basis for inhibition of the replication licensing factor Cdt1 by geminin. Centre- surround inhibition among olfactory bulb glomeruli
- Abstracts: Bose-Einstein condensation of the triplet states in the magnetic insulator TICuCI3. Cold ions in the hot plasma sheet of Earth's magnetotail
- Abstracts: Wave acceleration of electrons in the Van Allen radiation belts. Young stars go cruising by