Timing of neurotransmission at fast synapses in the mammalian brain
Article Abstract:
High calcium influx at the granule cell to stellate cell synapses in mammalian brain, during action potential upstroke, decreases the delay between depolarization and calcium entry from 150 to 90 microseconds. This in turn leads to faster transmission between the synapses. An increase in the temperature reduces the calcium currents and presynaptic action potentials duration, and the calcium entry latency. The molecular mechanisms which lead to calcium triggered exocytosis are also very fast.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
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Locally dynamic synaptic learning rules in pyramidal neuron dendrites
Article Abstract:
An analysis of coupling between plasticity at nearby synapses to determine the impact of long-term potentiation (LTP) of synaptic transmission on the potentiation at neighboring synapses, is described. It is inferred that LTP at individual synapses minimizes the threshold for potentiation at neighboring synapses in mouse hippocampal pyramidal cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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