Homeodomain-mediated [beta]-catenin-dependent switching events dictate cell-lineage determination
Article Abstract:
An unexpected strategy for [beta]-catenin-dependent regulation of cell-lineage determination based on interactions between [beta]-catenin and a specific homeodomain factor, Prop1, is presented. A novel transcriptional strategy that underlies [beta]-catenin control of cell-lineage determination in organogenesis is discovered during the study.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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CAMTA in cardiac hypertrophy
Article Abstract:
Calmodulin binding transcription activator 2 (CAMTA2) is an indispensable transcription coactivator for cardiac hypertrophy. CAMTA2 is activated by the disassociation of class II histone deacetylase 5 and promotes transcription of genes involved in cardiac hypertrophy through its interaction with Nkx2-5
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
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