A role for insect galectins in parasite survival
Article Abstract:
The exploitation of insect galectins, which are associated with embryonic developments by parasites for survival in their insect hosts, is shown. PpGalec, a tandem repeat galectin expressed in the midgut of the sand fly Phlebotomus papatasi, is used by Leishmania major as a receptor for mediating specific binding to the insect midgut, an event crucial for parasite survival and accounts for species-specific vector competence.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos
Article Abstract:
The study provides three lines of evidence that the pathway specifying the dorsal axis is activated extracellulary in Xenopus embryos. It is shown that Wnt11 is necessary and sufficient for axis specification upstream of beta-catenin and heparan sulfate proteoglycan (HSPG) and FRL1 may be cofactors for Wnt11 in the context of the axis initiation pathway.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Sex and death: What is the connection?
Article Abstract:
The relationship between sex and death is investigated with reference to the effects of insulin/IGF signaling (IIS) and dietary restriction (DR) on the life span and fecundity in C. elegans and Drosophila. The findings suggest that the life span gets extended and fecundity gets reduced due to dietary restrictions.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Signals for death and survival: a two-step mechanism for cavitation in the vertebrate embryo. Caspase activation: revisiting the induced proximity model
- Abstracts: Genetic clines in the Bay of Biscay provide estimates of migration for Sardina pilchardus. An ancient RNase HI splice junction mutant preserved in a 19-million-year-old genetic fossil in ape genomes
- Abstracts: From modulator to mediator: rapid effects of BDNF on ion channels
- Abstracts: Diversity and classification of mycorrhizal associations. Vegetation dynamics-simulating responses to climatic change
- Abstracts: Why repetitive DNA is essential to genome function. Dietary fats and membrane function: Implications for metabolism and disease