Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes
Article Abstract:
The naturally occurring antisense RNAs present in eukaryotic cells were described to explain the various ways in which the double-stranded RNAs (dsRNAs) influenced gene expression and the manner by which the cells reacted to the presence of dsRNAs. The naturally occurring antisense RNAs in higher eukaryotes were the short or imperfect duplex RNA and the long or perfect duplex RNA. It was established that dsRNAs were usually formed in almost all viral infections and they activated the synthesis of interferon. However, dsRNAs may possibly hinder the cellular synthesis of proteins.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 1998
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Effects of length and location on the cellular response to double-stranded RNA
Article Abstract:
The cellular responses to double-stranded RNA (dsRNA) would be natural and perhaps ancient antiviral responses. The main aim is to outline the current understandings of the fate of dsRNA in cells, with a focus on the apparent fact that their fates and functions appear to depend on where in the cell dsRNA molecules are found, and also on how long they are and perhaps on how abundant they are.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2004
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CO-sensing mechanisms
Article Abstract:
The physiological effects of carbon monoxide on organisms ranging from bacteria to humans are detailed. Emphasis is placed on the molecular description of CooA, a heme-containing CO sensor from Rhodospirillum rubrum, as its biological role as a CO sensor is clear and the basis of its sensing ability is also fine.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2004
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