CRIg: A macrophage Complement Receptor required for phagocytosis of circulating pathogens
Article Abstract:
The identification and characterization of a Complement Receptor of the Immunoglobulin superfamily, CRIg, that binds complement fragments C3b and iC3b is reported. CRIg represents a dominant component of the phagocytic system responsible for rapid clearance of C3-opsonized particles from the circulation.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
Article Abstract:
770 mostly novel protein-protein interactions were identified using a stringent yeast two-hybrid screen. The protein-protein interaction network was developed for the 20 or more different inherited cerebellar ataxias characterized by Purkinje cell degeneration.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment
Article Abstract:
The synapse targeting process follows the establishment of a subcellular gradient of neurofascin 186. Results implicate ankyrin-based localization of L1CAMS in subcellular organization.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus. The DExH box protein Suv3p is a component of a yeast mitochondrial 3'-to-5' exoribonuclease that suppresses group I intron toxicity
- Abstracts: G proteins are required for spatial orientation of early cell cleavages in C. elegans embryos. The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus
- Abstracts: Prohibitions control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria
- Abstracts: Development of unique house mouse resources suitable for evolutionary studies of speciation. Allelic melanism in American and British peppered moths
- Abstracts: Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation