Bean dwarf mosaic geminivirus movement proteins recognize DNA in a form- and size-specific manner
Article Abstract:
A study was undertaken to evaluate the DNA binding properties of the BV1 and BC1 proteins of the bean dwarf mosaic geminivirus to correlate them to the maintenance of the viral genome size during systemic infection. BV1 and BC1 are considered as movement proteins since the former moves viral DNA out of the nucleus and the latter influences DNA transport through plasmodesmata. Results revealed that the two proteins were capable of recognizing DNA on the basis of genome size and form and manifested protein-nucleic acid interaction.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?
Article Abstract:
The binding of proteoglycans to growth factors induces a regulatory role on the growth factors. The binding of the proteoglycan, heparin, to the fibroblast growth factor (FGF) is necessary for FGF-induced biological activity. Proteoglycans are proteins containing carbohydrates and are low affinity receptors. The binding of the low affinity receptors appears to be necessary for reducing the dimensionality of ligand binding from three to two dimensions.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Close similarity between Drosophila neurexin IV and mammalian Caspr protein suggests a conserved mechanism for cellular interactions
- Abstracts: Anti-neural-inhibition: a conserved mechanism for neural induction. %% trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry
- Abstracts: Aeromonas hydrophila isolated from food and drinking water: hemagglutination, hemolysis, and cytotoxicity for a human intestinal cell line (HT-29). part 2
- Abstracts: Hypothesis - can UV produced by intracellular bacteria cause cancer? Growth of green sulphur bacteria in experimental benthic oxygen, sulphide, pH and light gradients
- Abstracts: The flagellin N-methylase gene fliB and an adjacent serovar-specific IS200 element in Salmonella typhimurium. Identification of a 95 kDa putative adhesin from Actinomyces serovar WVA963 strain PK1259 that is distinct from type 2 fimbrial subunits