The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor
Article Abstract:
Kaiso, a p120 catenin partner, has been found to be a DNA methylation-dependent transcriptional repressor. A novel mammalian DNA binding activity that must have at least two symmetrically methylate CpG dinucleotides in its recognition sequence, preferably in the sequence 5'CGCG is described. Zinc-finger motifs appear to be responsible for DNA binding.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Identification and purification of two distinct complexes containing the five RAD51 paralogs
Article Abstract:
Identification and purification has been carried out for two distinct complexes containing the five RAD51 paralogs. The extreme sensitivity of paralog-defective cell lines to cross-linking agents has been found to be traceable to defects in the processing of incised cross links and to resulting failure to start recombinational repair at certain sites.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Identification of human and animal adenoviruses and polyomaviruses for determination of sources of fecal contamination in the environment
- Abstracts: Vertical distribution and phylogenetic characterization of marine planktonic Archaea in the Santa Barbara channel
- Abstracts: Genetics and cytology of a genic male-sterile, female-sterile mutant from a transposon-containing soybean population
- Abstracts: Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development
- Abstracts: Identification and expression of benzylsuccinate synthase genes in a toluene-degrading methanogenic consortium