Initial hydrogenation during catabolism of picric acid by Rhodococcus erythropolis HL 24-2
Article Abstract:
Rhodococcus erythropolis strain 24-2 is capable of utilizing 2,4-dinitrophenol (2,4-DNP) as the sole nitrogen source, through reactions which may involve nucleophilic attack. To further elucidate this process, a mutant strain of HL 24-2, designated HL PM-1, with the ability to utilize picric acid as nitrogen source, was characterized. The results showed that the initial metabolite of picric acid metabolism is a hydride-Meisenheimer complex of picric acid which is subsequently converted to nitrite and 2,4,6-trinitrocyclohexanone. These results indicate that the metabolism of 2,4-DNP and picric acid is initiated by a nucleophilic attack.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1992
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A new 4-nitrotoluene degradation pathway in a Mycobacterium strain
Article Abstract:
A new pathway was studied for the degradation of 4-nitrotoluene (4-NT) by a Mycobacterium strain which was isolated from a mixed soil sample from the Stuttgart area. Resting cells of the Mycobacterium strain metabolized 4-NT with concomitant release of small amounts of ammonia under aerobic conditions. Under anaerobic conditions, 4-NT was completely converted to 6-amino-m-cresol. Cell extracts converted 4-hydroxylaminotoluene to 6-amino-m-cresol and could be confirmed as the initial metabolite in the pathway.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1998
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Degradation of 2,4-dinitrophenol by two Rhodococcus erythropolis strains, HL 24-1 and HL 24-2
Article Abstract:
Two Rhodococcus erythropolis strains, designated HL 24-1 and HL 24-2, were enriched from soil and river water using 2,4-dinitrophenol (2,4-DNP). Characterization of the two strains showed that both could utilize 2,4-DNP as the sole source of nitrogen and carbon. Stoichiometric analysis showed that both strains metabolized 2,4-DNP through reactions producing nitrite and 4,6-dinotrohexanoate as end products.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1992
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