Intraflagellar transport and cilium-based signaling
Article Abstract:
Cilia are assembled and maintained by the intraflagellar transport (IFT) machinery, which coordinates rapid, bidirectional transport between the cell body and the distal tip of the cilium. Further research is required to understand precisely how the IFT machinery performs its critical roles in cilium-based signaling.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
p38 and a p38-interacting protein are critical for downregulation of e-cadherin during mouse gastrulation
Article Abstract:
A demonstration is presented that p38 MAP kinase and a p-38 interacting protein (p38IP) are critically required for downregulation of E-cadherin during gastrulation. It is shown that p38IP binds directly to p38 and is required for p38 activation in vivo.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development
Article Abstract:
RPM-1 that negatively regulates a p38 MAP kinase pathway composed of the dual leucine zipper-bearing MAPKKK DLK-1, the MAPKK MKK-4, and the p38 MAP kinase PMK-3, is reported. A presynaptic role of a previously unknown p38 MAP kinase cascade is revealed.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Lateral and axial signals involved in avian somite patterning: a role for BMP4. The divergent robo family protein Rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons
- Abstracts: Cotranscriptional Set2 methylation of histone H3 kysine 36 recruits a repressive Rpd3 complex. Navigating the chaperone network: An integrative mediated by the Hsp90 chaperone
- Abstracts: Glycosylation in cellular mechanisms of health and disease. Identification of two proteins required for conjunction and regular segregation of achiasmate homologs in Drosophila male meiosis
- Abstracts: Cotranscriptional Set2 methylation of histone H3 kysine 36 recruits a repressive Rpd3 complex. part 2 Mapping global histone acetylation patterns to gene expression
- Abstracts: Reliable and rapid identification of Listeria monocytogenes and Listeria species by artificial neural network-based Fourier transform infrared spectroscopy