Mesoderm induction and axis determination in Xenopus laevis
Article Abstract:
Inductive cell interactions of peptide growth factors determine mesoderm formation and establish the dorsoventral axis in Xenopus laevis embryos. Animal explant assays show that fibroblast growth factors predominantly act as ventrolateral inducers while the transforming growth factor-beta homolog activin induce dorsal-to-ventral mesoderm patterning. In addition, RNA injection assay indicate that members of the Wnt protein family possess dorsalizing effects. Inducers activate regulatory genes in the Spemann organizer in Xenopus gastrulae one of which is the homeobox genes goosecoid.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
RNA-binding proteins: masking proteins revealed
Article Abstract:
Oocyte-abundant proteins do not only function as RNA-binding and -protecting molecules but also as transcription factors. In particular, p56 and p60 have been discovered to belong to the Y-box family, transcription proteins with a CCAAT box. mRNA-masking proteins interact with DNA and RNA molecules in separate binding domains. RNA molecules are bound by hydrogen-binding side chains and its regulation is accomplished by methylation and phosphorylation. Protein-masking leads to stabilization of ribonuleoproteins in oocytes, RNA transport and mRNA localization.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
The potential for the formation of the arginine biosynthetic enzymes and its masking during evolution
Article Abstract:
The article presents a detailed analysis of the history of the arginine biosynthetic enzyme. The results reveal that the added, as well as the internally produced arginine highly represses the enzyme formation, as the potential required for this enzyme synthesis is found to be in excess of what is required.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Removal indeterminacy and the proximate determination of clutch size in the House Sparrow. Effects of water conditions on clutch size, egg volume, and hatchling mass of Mallards and Gadwalls in the Prairie Pothole Region
- Abstracts: A PCR detection method for rapid identification of Paenibacillus larvae. Characterization of bacterial and fungal soil communities by automated ribosomal intergenic spacer analysis fingerprints: biological and methodological variability
- Abstracts: Construction and characterization of a 1,3-propanediol operon. Use of an ipb-lux fusion to study regulation of the isopropylbenzene catabolism operon of Pseudomonas putida RE204 and to detect hydrophobic pollutants in the environment
- Abstracts: Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Structure, expression, chromosomal location and product of the gene encoding ADH2 in Petunia
- Abstracts: The evolution of tandemly repetitive DNA: recombination rules. part 2 Molecular analysis of lambda bio transducing phage produced by oxolinic acid-induced illegitimate recombination in vivo