Molecular analysis of the cso operon of enterotoxigenic Escherichia coli reveals that CsoA is the adhesin of CS1 fimbriae and that the accessory genes are interchangeable with those of the cfa operon
Article Abstract:
The CsoA protein, a bacterial antigen, functions as an adhesin in the CS1 fimbriae of enterotoxigenic Escherichia coli. The removal of the csoA gene suppresses fimbrial adhesion. Complementation in trans, encoding CsoA, restores the adhesion activity of CS1. The suppression is also removable by complementation with the cfaB gene which encodes the CfaB adhesive protein of CFA/I fimbriae. The open reading frames (ORFs) of the csoA gene encode structurally similar proteins to those encoded by the ORFs of the cfa operon.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
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Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection
Article Abstract:
A study was conducted to analyze the characterization of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection. A mouse model of ascending urinary tract infection was utilized to carry out the analysis. In addition, chromosomal DNA from P. mirabilis transposon mutants was digested with restriction enzymes before being electrophoresed on an agarose gel.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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The Pix pilus adhesin of the uropathogenic Escherichia coli strain X2194 (O2:K(sup)-:H6) is related to pap pili but exhibits a truncated regulatory region
Article Abstract:
The unique filamentous adhesin from the clinical isolate of Escherichia coli uses pilus for its adhesion and hence referred to as 'Pix'. Data indicate that the Pix adhesin possesses genetic and structural characteristics of pap pilus but lacks a papI equivalent. However it exhibits R6 gene fragment that is involved in the expression of Pix pili.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2003
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