New rods move before differentiating in adult teleost retina
Article Abstract:
Neuronal differentiation of the vertebrate retina can be analyzed through the following experiment. The progenitor cells in teleost retina are located adjacent to the outer retinal membrane and divide near the scleral border after which they move inwards toward the vitreal boundary of the outer nuclear membrane. The differentiation of these progenitor cells into rod photoreceptors takes place after this movement which is seen even in adult retinae. The results of the study suggest that only one of the progenitor daughter cells moves inward while the other remains in its original position and re-divides.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 1995
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Identification of a neural stem cell in the adult mammalian central nervous system
Article Abstract:
New neurons which are continuously added in certain regions of the adult mammalian brain and are thought to originate from a population of multipotent stem cells have the capacity for self-renewal and can generate the major classes of central nervous system cell types. These cell types are neurons, astrocytes and oligodendrocytes. A study demonstrates that ependymal cells are neural stem cells and provides novel insights into how stem cells participate in the response to central nervous system injury.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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Differentiation of hippocampal progenitor cells in vitro: temporal expression of intercellular coupling and voltage- and ligand-gated responses
Article Abstract:
Examination of immortalized murine embryonic hippocampal progenitor cells upon treatment with interleukin-7 added alone or concurrently with transforming growth factor-alpha and basic fibroblast growth factors, by dye coupling, patch clamp and Ca(2+)- imaging techniques, reveals the temporal relationship among the expression of neuronal gap junctions and the onset of voltage- and ligand-gated responses. Expression of gap junctions in neuronal progenitor cells occurs during early ontogeny.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 1995
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