Novel signaling from the peripodial membrane is essential for eye disc patterning in Drosophila
Article Abstract:
Results demonstrate that the epithelium peripodial membrane secreted proteins are required for the development and pattern formation in the eye of Drosophila as shown by disruption of disc growth in the absence of one of the proteins secreted by peripodial membrane.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
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Peripodial cells regulate proliferation and patterning of Drosophila imaginal discs
Article Abstract:
Research reveals that squamous epithelium peripodial membrane covers columnar cell monolayers of imaginal discs and are involved in cell signaling that leads to growth and pattern formation in the eye and wing primordia of Drosophila.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
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Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity
Article Abstract:
A novel Drosophila protein called Discs Lost (DLT) was identified. Its main function, which concerns the polarization of embryonic epithelia during cellular blastoderm formation, is achieved by interacting with the apical determinant Crumbs and the localized protein Neuroxin IV. The DLT protein is also observed to have a critical role in establishing and maintaining cell polarity. Furthermore, it is involved in different molecular complexes that characterize apical and lateral membrane domains.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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