Post-transcriptional regulation of RNA polymerase II level in Caenorhabditiselegans

Article Abstract:

Caenorhabditis elegans strains containing one to three copies of the gene ama-1 which codes for the largest subunit of RNA polymerase II were constructed to study the regulation of the enzyme level. The levels of RNA polymerase II and enzymatic activity were found to be independent of gene dosage. On the other hand, RNA polymerase II messenger RNA levels was directly proportional to the number of ama-1 copies. This is suggestive of a post-transcriptional regulation of enzyme levels.

Physiological aspects, RNA polymerases

---

Heritable variation and mutagenesis at early International Congresses of Genetics

Article Abstract:

Papers on heritable variation were submitted at various editions of the International Congresses of Genetics. These studies paved the way for more research on the mechanisms of DNA repair and mutagenesis. The first paper on mutagenesis ever submitted to the conference was H.J. Muller's 1927 report on his X-ray research. Meanwhile, three studies were discussed at the 1939 congress that elucidated the relationship between ultraviolet action spectra and induced mutagenesis.

Gene mutations, Gene mutation, Variation (Biology), Mutagenesis, International Congress of Genetics

---

Genes that regulate both development and longevity in Caenorhabditis elegans

Article Abstract:

Response characteristics to the scarcity of food and over population conditions is exhibited by the nematode Caenorhabditis elegans as the retardation in the growth of the nematode. The retardation results in the dauer lareval stage. The mutations which alter dauer larva formation on genetic analysis reveal that the dauer larva formation (daf) mutations, the daf-23 and daf-2 genes are the primary cause for the response.

Nematoda, Nematodes

Similar abstracts:

• Abstracts: Characterization of Caenorhabditis elegans lectin-binding mutants. Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase
• Abstracts: Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Structure, expression, chromosomal location and product of the gene encoding ADH2 in Petunia
• Abstracts: Localization and characterization of alpha-glucosidase activity in Brettanomyces lambicus. Isolation of auxotrophic mutants of diploid industrial yeast strains after UV mutagenesis
• Abstracts: LODs past and present. Regulation of DNA polymerase exonucleolytic proofreading activity: studies of bacteriophage T4 "antimutator" DNA polymerases

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.