Rho is a presynaptic activator of neurotransmitter release at pre-existing synapses in C. elegans

Article Abstract:

The effect of Rho-inlfuencing transgenes on acetylcholine (ACh) release at the Caenorhabditis elegans neuromuscular junction is examined to investigate the role of Rho in regulating neurotransmitter release. The single C. elegans Rho ortholog (RHO-1) is expressed throughout the nervous system and is required for normal cell migration, cell shape regulation and neurite outgrowth.

United States, Cell migration, Neurotransmitters

---

Trio's Rho-specific GEF domain is the missing G[[alpha].sub.q] effector in C. elegans

Article Abstract:

A study providing the first insights into the relative importance of the RhoGEF and PLC[beta] G[[alpha].sub.q] effector pathways in the context of a living animal is presented. Rho-specific GEF domain is an important G[[alpha].sub.q] effector that along with PLC[beta], mediates the G[[alpha].sub.q] signaling.

G proteins

---

Rho deep in thought

Article Abstract:

Recent studies reveal that Rho GTPases have a major role to play in the neural development as well as regulating neuronal activity in the adult brain, at least in Caenorhabditis elegans.

Neurons

Similar abstracts:

• Abstracts: The bZip proteins CES-2 and ATF-2 alter the timing of transcription for a cell-specific target gene in C. elegans
• Abstracts: On the trail of a point mutation: The discovery of a blood-cancer gene raises tantalizing questions
• Abstracts: The strength of selection on ultraconserved elements in the human genome
• Abstracts: Chitinolytic Enterobacter agglomerans antagonistic to fungal plant pathogens. Trichoderma mitogen-activated protein kinase signaling is involved in induction of plant systemic resistance
• Abstracts: There's an art to creating - and selling - a life science company

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.