Specific isoforms of squid, a 'Drosophila' hnRNP, perform distinct roles in gurken localization during oogenesis
Article Abstract:
Squid (sqd), a Drosophila melanogaster gene, is key in localization and translational regulation of mRNAs. Mutations to sqd proteins can cause sterility in females due to gurken mislocation during oogenesis. SqdA is primarily cytoplasmic, while SqdB and SqdS are primarily located in germ-line nuclei. Differential nuclear accumulation corresponds with association of nuclear import proteins.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1999
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Deadlock, a novel protein of Drosophila, is required for germline maintenance, fusome morphogenesis and axial patterning in oogenesis and associates with centrosomes in the early embryo
Article Abstract:
The role of deadlock gene mutations in promoting germline cell maintenance, mitotic spindle stability, oocyte growth, biogenesis, and other key developments during oogenesis in Drosophila mutant embryos, is analyzed.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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Multiple EGFR ligands participate in guiding migrating border cells
Article Abstract:
The role epidermal growth factor receptor and poliovirus receptor ligands in guiding migration of border cells in Drosophila melanogaster ovary, during embryonic development, is analyzed.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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