Structure and biogenesis of the capsular F1 antigen from Yersinia pestis: preserved folding energy drives fiber formation
Article Abstract:
Research shows that during fiber formation in Yersinia pestis, chaperone protein traps a high-energy folding intermediate of capsular F1 antigen sububit , which upon release completes the folding. Furthermore, comparison of chaperone bound capsular F1 antigen with the fiber subunit reveals a conformational change that involved the full hydrophobic core of the protein.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
Article Abstract:
Results point out that the human winged helix/forkhead transcription factor gene FOXC2 regulates adipocyte metabolism, which lead to lean and insulin sensitive phenotype. Data indicate that high fat diet enhancement of FOXC2 levels counteract symptoms of obesity, hypertriglyceridemia, and insulin resistance.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands
Article Abstract:
Research has been conducted on neural cell adhesion molecule NCAM. The authors demonstrate that this molecule functions as a signaling receptor for the members of the glial cell line-derived neurotrophic factor ligand family.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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- Abstracts: Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori. Identification of a 29 kDa flagellar sheath protein in Helicobacter pylori using a murine monoclonal antibody
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