Synaptic circuitry of the retina and olfactory bulb
Article Abstract:
The circuitry and synaptic mechanisms of the retina and olfactory bulb are discussed, with emphasis on recent advances and studies which shed light on the workings of other regions of the nervous system. Most of the recent findings are derived from studies of microelectrode recordings from single neurons, which have been useful in elucidating receptive field organization of retinal ganglion cells and odorant responses of mitral cells in the olfactory bulb. Future research will focus on the spatial and temporal resolution of cell population activity.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1993
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Olfactory inputs to hypothalamic neurons controlling reproduction and fertility
Article Abstract:
A study in identifying afferent pathways to neurons synthesizing luteinizing hormone-realizing hormone (LHRH) a key neurohormone of reproduction aimed to gain insight into sensory processing modulating behaviour and endocrine changes. The results identify major olfactory projection pathways originating from a discrete population of olfactory sensory neuronsbut fail any synaptic connectivity with the vomeronasal system in contrast to established notions of the nature of LHRH neuronal inputs.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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PDZ proteins organize synaptic signalling pathways
Article Abstract:
Membrane-associated guanylate kinases (MAGUKs) contain PDZ domains in their amino termini. MAGUKs have been shown to be responsible for receptor, channel and synaptic structure in the neuromuscular junction of Drosophila. These proteins are responsible for interactions between proteins mediated through short segments of the carboxy termini of receptors and channels. The mechanism of protein recruitment to synapses during development remains to be elucidated.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
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