The QUTA activator and QUTR repressor proteins of Aspergillus nidulans interact to regulate transcription of the quinate utilization pathway genes
Article Abstract:
The activity of the QUTR transcription repressor protein in the quinic acid utilization pathway of Aspergillus nidulans nullifies the action of the QUTA activator protein. Genetic analyses suggest three mechanisms of action of the QUTR protein. The first indicates that high levels of QUTR protein result in the formation of another protein that interacts with QUTA protein to inactivate it. The second possibility is the production of a pool of organic molecules that inactivate QUTA and the third is an inactivating effect through a protein-protein interaction with the QUTA protein.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
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A pre-induction sporulation gene from Aspergillus nidulans
Article Abstract:
The developmental process of asexual sporulation in Aspergillus nidulans is controlled by genes which act before and after the application of the inductive stimulus. The acoB gene is probably required for sporulation at high temperatures and hybridization of acoB DNA with DNA from many Aspergillus species indicates a similarity of the gene to sexually sporulating species belonging to the nidulans group. AcoB is a pre-induction gene, disruption of which produces a strain that is sensitive to temperature.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1995
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Changes in Aspergillus nidulans gene expression induced by bafilomycin, a Streptomyces-produced antibiotic
Article Abstract:
A study was conducted to analyze the response of the filamentous fungus Aspergillus nidulans to the antibiotic bafilomycin B1. mRNA differential display was utilized to examine changes in fungal gene expression. A. nidulans was harvested on filter paper. Differential display was then carried out based on the RNAmap mRNA Differential Display system. Results indicated that the antibiotic promoted changes in the abundance of the corresponding mRNA.
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
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