The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Ga14
Article Abstract:
The Saccharomyces cerevisiae SAGA (Spt-Ada-Gen5-Acetyltransferase) complex has been found to act as a coactivator for transcriptional activation by Ga14 in vivo. Ga14-NP16 was also found to recruit SAGA in vivo. A specific interaction between Spt3 and TBP in vivo appears to be important for Ga14 transcriptional activation after SAGA recruitment. SAGA is a large multiprotein complex needed for normal transcription of many genes.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Activation of dormant origins of DNA replication in budding yeast
Article Abstract:
Activation of dormant origins of DNA replication is discussed relative to budding yeast. It is shown that dormant replication origins on the left arm of budding yeast chromosome III are activated when two things happen. Both passive replication through them must be prevented and the Mec1/Rad53 checkpoint that blocks late-origin firing must be inactivated.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action
Article Abstract:
Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride is discussed with attention to insights into activator mechanochemical action. Energy transduction seems to occur through activator contacts of sigma 54 Region I.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo
- Abstracts: In vivo analysis of a developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein
- Abstracts: Posttranscriptional control of gene expression in yeast. Functional interactions between a phage histone-like protein and a transcriptional factor in regulation of phi29 early-late transcriptional switch
- Abstracts: Interspecific pollen competition and reproductive isolation in Iris. Age-specific fitness components in hybrid females of Drosophila pseudoobscura and D. persimilis
- Abstracts: The acid-stress response in Lactobacillus sanfranciscensis CB1. A mutation that affects fibril protein, development, cohesion and gene expression in Myxococcus xanthus